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Allele : Kit<W-44J> KIT proto-oncogene receptor tyrosine kinase; dominant spotting 44 Jackson

Primary Identifier  MGI:1856247 Allele Type  Spontaneous
Gene  Kit Inheritance Mode  Semidominant
Strain of Origin  C3H/HeJ Is Recombinase  false
Is Wild Type  false
molecularNote  Southern hybridization analyses of genomic DNA using probes corresponding to two specific lengths of amino acids from c-kit suggests that this allele comprises a 4-5 kb insertion that disrupts c-kit. The level of c-kit mRNA in homozygotes is markedly reduced.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

4 Publication categories