| Primary Identifier | MGI:1856424 | Allele Type | Spontaneous |
| Attribute String | Null/knockout | Gene | Lep |
| Inheritance Mode | Recessive | Strain of Origin | STOCK Mlph<ln> a Tgfa<wa1> Cdh23<v> Ednrb<s> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Sequencing of RT-PCR products revealed a nonsense mutation in arginine codon 105 (p.R105*) resulting from a C-to-T point mutation. The 16 kDa leptin protein, expressed predominantly in adipose tissue of normal mice, is missing from homozygous mutant mice (J:29081). |
