| First Author | Hayasaka I | Year | 1980 |
| Journal | Jikken Dobutsu | Volume | 29 |
| Issue | 4 | Pages | 391-5 |
| PubMed ID | 7202526 | Mgi Jnum | J:12736 |
| Mgi Id | MGI:60956 | Doi | 10.1538/expanim1978.29.4_391 |
| Citation | Hayasaka I, et al. (1980) Polydactyly Nagoya, Pdn: A new mutant gene in the mouse. Jikken Dobutsu 29(4):391-5 |
| abstractText | A new hereditary polydactyly (gene symbol Pdn) was found in the course of breeding JCL : ICR mice. The genetic analysis indicated that the polydactyly was an autosomal dominant trait. The homozygotes died within two days after birth. The homozygous fetuses or newborn had 1-3 extra-digits both in te fore- and hindlimbs on the preaxial side. They occasionally showed exencephaly, cleft palate, open eyelid, short tibia and fibula or deformed sternum. The heterozygotes had one extra-digit preaxial side. They occasionally showed exencephaly, heterozygotes had one extra-digit preaxially in the hindlimb and an enlarged first digit on the forelimb which often showed bifurcated distal phalanx. A tab on the postaxial side of the forelimb was found in all homozygotes and in some heterozygotes. |
