|  Help  |  About  |  Contact Us

Allele : Grem1<ld-J> gremlin 1, DAN family BMP antagonist; limb deformity Jackson

Primary Identifier  MGI:1856290 Allele Type  Spontaneous
Gene  Grem1 Inheritance Mode  Recessive
Strain of Origin  CBA/Ca-Bmp5<se> Is Recombinase  false
Is Wild Type  false
molecularNote  A G-to-A transition mutation at the boundary between intron 1 and exon 2 disrupts pre-mRNA splicing by eliminating the AG motif at the 3' splice acceptor site. The aberrant transcript expressed by this allele has a 65 base deletion of the 5' part of exon 2 and is missing the translational start codon.
  • mutations:
  • Single point mutation
  • synonyms:
  • Fmn<ld-J>,
  • ld<J>,
  • ld<J>,
  • Fmn<ld-J>,
  • footless,
  • footless
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

Trail: Allele

0 Driven By

14 Publication categories

Trail: Allele