| Primary Identifier | MGI:1856301 | Allele Type | Spontaneous |
| Gene | Tyr | Inheritance Mode | Recessive |
| Strain of Origin | SELH/Bc | Is Recombinase | false |
| Is Wild Type | false |
| description | Tyrc-Bc, albino British Columbia, recessive. This spontaneous mutation arose in a male that appeared to be a somatic and germ line mosaic for the new albino allele. Homozygotes die soon after implantation. There is no activity of the Mod2 allele in cis with Tyrc-Bc, and it is concluded that this mutation represents a deletion including the Tyr locus, Mod2, and a hypothetical locus essential for postimplantation survival (J:62). The Tyrc-Bc mutation is a deletion of exons 1, 2, and 3, along with other Chr 7 loci (J:18053). |
| molecularNote | This allele involves a deletion of as much as 2 cM including exons 1, 2, and 3 of Tyr, the Mod-2 locus and a gene essential for postimplantation survival. |
