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Publication : Expression of utrophin at dystrophin-deficient neuromuscular synapses of mdx mice: a study of protected and affected muscles.

First Author  Ferretti R Year  2011
Journal  Anat Rec (Hoboken) Volume  294
Issue  2 Pages  283-6
PubMed ID  21235003 Mgi Jnum  J:175589
Mgi Id  MGI:5286052 Doi  10.1002/ar.21297
Citation  Ferretti R, et al. (2011) Expression of utrophin at dystrophin-deficient neuromuscular synapses of mdx mice: a study of protected and affected muscles. Anat Rec (Hoboken) 294(2):283-6
abstractText  In mdx mice, intrinsic laryngeal muscles are spared and sternomastoid muscles are affected, showing cycles of muscle regeneration. We observed that utrophin and acetylcholine receptors are fragmented only in affected muscles, providing further evidence that changes in the overall distribution of molecules at dystrophic neuromuscular junctions may be correlated with muscle regeneration.
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