Primary Identifier | MGI:1856512 | Allele Type | Spontaneous |
Gene | Kit | Inheritance Mode | Semidominant |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Analysis of cDNA showed this allele comprises a C-to-T transition at nucleotide 2504 (transcript NM_021099) in the tyrosine kinase domain, resulting in a change of alanine to valine at position 835 (p.A835V). Encoded c-kit protein is not expressed on the cell surface. |