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Allele : Kit<W-n> KIT proto-oncogene receptor tyrosine kinase; Nagoya dominant spotting

Primary Identifier  MGI:1856512 Allele Type  Spontaneous
Gene  Kit Inheritance Mode  Semidominant
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Analysis of cDNA showed this allele comprises a C-to-T transition at nucleotide 2504 (transcript NM_021099) in the tyrosine kinase domain, resulting in a change of alanine to valine at position 835 (p.A835V). Encoded c-kit protein is not expressed on the cell surface.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories