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Publication : Changes in expression of glutamate receptor subunits following photoreceptor degeneration in the rd mouse retina.

First Author  Duvoisin RM Year  1995
Journal  Neurosci Lett Volume  183
Issue  1-2 Pages  83-6
PubMed ID  7538211 Mgi Jnum  J:23068
Mgi Id  MGI:70792 Doi  10.1016/0304-3940(94)11120-8
Citation  Duvoisin RM, et al. (1995) Changes in expression of glutamate receptor subunits following photoreceptor degeneration in the rd mouse retina. Neurosci Lett 183(1-2):83-6
abstractText  The effects of photoreceptor cell degeneration on the expression of nine alpha-amino-3-hydroxy-5-methyl-isoxasole-4-propionate (AMPA)/kainate glutamate receptor subunit genes were investigated in the rd mouse retina by in situ hybridization. All known AMPA/kainate receptor subunits were found to be expressed in normal mouse retina. Following retinal degeneration, the expression of KA-1 was reduced, that of the GluR7 subunit was greatly increased, and that of the other seven subunits were not significantly affected.
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