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Publication : Ambiguus nucleus neurons innervating the abdominal esophagus are malpositioned in the reeler mouse.

First Author  Fujimoto Y Year  1998
Journal  Brain Res Volume  811
Issue  1-2 Pages  156-60
PubMed ID  9804938 Mgi Jnum  J:51051
Mgi Id  MGI:1314529 Doi  10.1016/s0006-8993(98)00910-x
Citation  Fujimoto Y, et al. (1998) Ambiguus nucleus neurons innervating the abdominal esophagus are malpositioned in the reeler mouse. Brain Res 811(1-2):156-60
abstractText  To examine whether the migration of ambiguus nucleus (NA) neurons is affected in the reeler mouse, recombinant replication-deficient adenoviral vector carrying E. coli-galactosidase gene (lacZ) was injected into the abdominal esophagus of the reeler mouse and normal control at two months of age prior to 5 days of sacrifice of the animals. In the normal control, lacZ-positive neurons were found in the compact formation of the NA, whereas, in the reeler, they were scattered from the base of the fourth ventricle to the ventro-lateral margin of the medulla. The present study confirmed that NA neurons are malpositioned in the reeler mouse, suggesting that the migration of NA neurons is guided by the reelin-related protein (Reelin). Copyright 1998 Elsevier Science B.V.
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