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Allele : Scn8a<med-TgA4Bs> sodium channel, voltage-gated, type VIII, alpha; motor end plate disease (TgA4Bs)

Primary Identifier  MGI:1856414 Allele Type  Transgenic
Gene  Scn8a Inheritance Mode  Recessive
Strain of Origin  (C57BL/6J x C3H)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  A 20kb deletion was detected at the transgene insertion site, with no evidence of additional rearrangement of the chromosomal DNA. This insertion and deletion cause expression of Scn8a to be disrupted. Expression from the inserted transgene was detected in the liver.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Scn8a<->,
  • Scn8a<med-tg>,
  • Scn8a<medtg>,
  • Scn8a<med-tg1>,
  • Med<Tg>Scn8a,
  • med<Tg>,
  • Scn8a<->,
  • Scn8a<med-tg1>,
  • Scn8a<med-tg>,
  • Med<Tg>Scn8a,
  • Scn8a<med-TgNA4Bs>,
  • Scn8a<med-TgNA4Bs>,
  • med<Tg>,
  • Scn8a<medtg>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

18 Publication categories