| First Author | Royaux I | Year | 1997 |
| Journal | Genomics | Volume | 42 |
| Issue | 3 | Pages | 479-82 |
| PubMed ID | 9205121 | Mgi Jnum | J:41458 |
| Mgi Id | MGI:893936 | Doi | 10.1006/geno.1997.4772 |
| Citation | Royaux I, et al. (1997) Reln(rl-Alb2), an allele of reeler isolated from a chlorambucil screen, is due to an IAP insertion with exon skipping. Genomics 42(3):479-82 |
| abstractText | The reeler Albany2 mutation (Reln(rl-Alb2) in the mouse is an allele of reeler isolated during a chlorambucil mutagenesis screen. Homozygous animals had drastically reduced concentrations of reelin mRNA, in which an 85-nt exon was absent. At the genomic level, the mutation was shown to be due to an intracisternal A-particle insertion leading to exon skipping. This appears to be the first observation of retrotransposon insertion during chlorambucil mutagenesis. |
