| First Author | Bronson RT | Year | 1990 |
| Journal | Brain Res Dev Brain Res | Volume | 54 |
| Issue | 1 | Pages | 131-6 |
| PubMed ID | 2364541 | Mgi Jnum | J:12732 |
| Mgi Id | MGI:60953 | Doi | 10.1016/0165-3806(90)90073-8 |
| Citation | Bronson RT, et al. (1990) Hydrocephalus with hop gait (hyh): a new mutation on chromosome 7 in the mouse. Brain Res Dev Brain Res 54(1):131-6 |
| abstractText | Hydrocephalus with hop gait (hyh) is a new lethal recessive mouse mutation that arose in the C57BL/10J strain at The Jackson Laboratory. It has been mapped to the proximal end of Chromosome 7 close to the Gpi-1 locus. This homozygous mutant is characterized clinically by a domed head and a hopping gait observable at 2 weeks of age and death between 4 and 10 weeks of age. The affected mice have dilated lateral ventricles and a large third ventricular cyst, patent through narrowed rostral cerebral aqueduct, cystic caudal aqueduct and no communication of the aqueduct with the fourth ventricle. The cerebellum has a mild cortical malformation. |
