Primary Identifier | MGI:1856573 | Allele Type | Spontaneous |
Gene | Espn | Inheritance Mode | Recessive |
Strain of Origin | fancier's dancing mouse | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A single nucleotide deletion (G) at position 2426 of the Espn gene results in a frameshift mutation and premature stop in the C-terminal actin binding domain. Normal levels of mRNA are observed, but no accumulation of protein is observed in the jerker mouse. |