| First Author | Wallace ME | Year | 1981 |
| Journal | Mouse News Lett | Volume | 65 |
| Pages | 11 | Mgi Jnum | J:13890 |
| Mgi Id | MGI:62068 | Citation | Wallace ME, et al. (1981) Curly-tail lethal. Mouse News Lett 65:11 |
| abstractText | Full text of MNL contribution: Research News: Peruvian mutants. Information on the mutants found in Peru-Coppock mice was last summarized in MNL 61, July 1979. New information and new mutants have accrued: Curly-tail lethal. The first specimen was seen in generation 3 of site 3, but it seemed to be a recessive with very poor penetrance, since some 5 upgradings brought almost no improvement. Further selection after crossing to at, gave, in 13 matings, 23 curlytails among 284; only 3 curly x curly were possible and were no better. However, most matings were noticed to be Aat x Aat, and these gave 31 AA : 130 Aat : 60 atat. It seemed that many of these could have been CylA/+at x CylA/+at, i.e. that curlytail could be a poorly penetrating dominant linked to A and lethal homozygously. By the rough process of discarding matings without a paucity of AA, an approximate estimate of recombination is 11%. Curlytail is being combined with other chromosome 2 markers. The symbol Cyl is agreed. (Wallace and Ferguson) |
