Primary Identifier | MGI:1856699 | Allele Type | Spontaneous |
Gene | Sharpin | Inheritance Mode | Recessive |
Strain of Origin | C57BL/Ka | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A single nucleotide deletion (C forward strand, G reverse gene strand; from sequence CCCC) in glycine codon 65 or alanine codon 66 in the 3' end of exon 1 creates a shift in the open reading frame at Ala66 (changing it to arginine) predicted to cause a premature stop codon 4 codons downstream. |