| Primary Identifier | MGI:1857025 | Allele Type | Spontaneous |
| Attribute String | Hypomorph | Gene | Tbx6 |
| Inheritance Mode | Recessive | Strain of Origin | C57L/J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | This hypomorphic allele contains a rearrangement in the promoter region. A 182 bp insertion 240 bp upstream of the translation initiation site includes part of exon 1, intron 1, and a portion of exon 2 in inverted orientation. Whole mount in situ hybridisation detected variable and less abundant transcript expression in homozygous mutant E9.5 embryos. |
