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Publication : Development of rib-vertebrae: a new mutation in the house mouse with accessory caudal duplications.

First Author  Theiler K Year  1985
Journal  Anat Embryol (Berl) Volume  173
Issue  1 Pages  111-6
PubMed ID  4073528 Mgi Jnum  J:8119
Mgi Id  MGI:56588 Doi  10.1007/BF00707309
Citation  Theiler K, et al. (1985) Development of rib-vertebrae: a new mutation in the house mouse with accessory caudal duplications. Anat Embryol (Berl) 173(1):111-6
abstractText  The new recessive mutation rib-vertebrae (rv) causes fusions of lower ribs and malformations of vertebrae, which results from disturbed somite arrangement. In addition, duplications of the caudal neural tube and sometimes unilateral suppression of kidney formation can be observed. The new mutation is compared with the six already known mutations in mice with Wirbel-Rippen-Syndrome and with a similar syndrome in man. From the various effects of the rv-gene observed, it is suggested that the gene causes abnormal inner and outer surface formation, producing manifold secondary effects.
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