First Author | Boufares S | Year | 1993 |
Journal | Physiol Behav | Volume | 53 |
Issue | 6 | Pages | 1151-5 |
PubMed ID | 8346298 | Mgi Jnum | J:14497 |
Mgi Id | MGI:62664 | Doi | 10.1016/0031-9384(93)90372-m |
Citation | Boufares S, et al. (1993) Restoration of staggerer mouse maternal behavior following long-term breeding selection. Physiol Behav 53(6):1151-5 |
abstractText | Two lines of staggerers from the C57BL/6 strain were tested for disturbances in maternal behavior and locomotion. One line, called Pasteur, included staggerers available at L'Institut Pasteur. The second line, called Selected, included staggerers that had been bred in our laboratory for several generations for their ability to reproduce. While none of the Pasteur animals showed any evidence of maternal behavior, most of the Selected mutant mice became maternal, carrying about 90% of the pups until weaning. No group differences were seen in locomotory behavior. It was concluded that a) as a result of long-term breeding selection, homozygous (sg/sg) animals of the C57BL/6 strain may be able to exhibit maternal behavior from birth on, even under standard laboratory conditions; b) the restoration of the maternal behavior does not equally affect all components of this behavior pattern; and c) the impairment of the maternal behavior showed by the staggerer females is not a necessary consequence of impaired locomotory capacity characteristic of the staggerer. |