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Allele : Pgap1<oto> post-GPI attachment to proteins 1; otocephaly

Primary Identifier  MGI:1856621 Allele Type  Radiation induced
Gene  Pgap1 Inheritance Mode  Recessive
Strain of Origin  STOCK In(1)1Rk/J Is Recombinase  false
Is Wild Type  false
description  This mutation was probably induced by X irradiation of a male homozygous for the Chr 1 inversion In(1)1Rk. Segregation among descendants of this male showed that oto is either within or closely linked to the inversion.
molecularNote  While no mutations could be identified in cDNA sequence, northern blot analysis confirmed reduced expression of Pgap1 protein in adult mutant tissue and E10.5 embryos. mRNA length is normal indicating the mutational event disrupts a regulatory region, attenuating transcription.
  • synonyms:
  • oto<xray>,
  • oto<xray>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories