| First Author | Korobova O | Year | 1998 |
| Journal | Genomics | Volume | 54 |
| Issue | 3 | Pages | 556-9 |
| PubMed ID | 9878259 | Mgi Jnum | J:52077 |
| Mgi Id | MGI:1327780 | Doi | 10.1006/geno.1998.5528 |
| Citation | Korobova O, et al. (1998) Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region. Genomics 54(3):556-9 |
| abstractText | Patchy fur is a semidominant X-linked mutation in the mouse, resulting in a sparse coat. The Paf mutation also alters the normal segregation of the X and the Y chromosomes during male meiosis by causing nondisjunction at anaphase I. Analysis of 1139 female meioses from an intersubspecific backcross using 15 PCR-based markers localizes Paf to an similar to 0.2-cM interval that includes the pseudoautosomal boundary. The meiotic nondisjunction phenotype may result from a chromosomal rearrangement that includes pseudoautosomal sequences and affects XY pairing. (C) 1998 Academic Press. |
