| First Author | Sorokina JD | Year | 1985 |
| Journal | Mouse News Lett | Volume | 73 |
| Pages | 23 | Mgi Jnum | J:14021 |
| Mgi Id | MGI:62199 | Citation | Sorokina JD, et al. (1985) Waved alopecia. Mouse News Lett 73:23 |
| abstractText | Full text of MNL contribution: 3. Waved alopecia - {preliminary symbol - wal) Ð spontaneous recessive autosomal mutation discovered in BALB/cLac strain at ÒStolbovaja" Farm. Mutant gene was localized on 14th chromosome between hr and s. There are 7.84 +/- 0.93% recombinations between hr and wal, and 5.62 +/- 0.93% recombinations between wal and s. Mutants are recognizable by their long waved fasciculated hair. Thin short hairs grow in by 1st month of age after juvenile shedding. To the 2nd month animal bodies appear hairless. The long waved hairs are keeping only on the head, particulary behind the ears and over the tail. The female mice have a higher incidence of shedding than the males. The Changes of vibrissae are not occured. Histologically there is irregulary skin thickness in mutants already at 1 week of age due to irregulary distribution of the hair follicles. All stages of the follicle degeneration are occured distinctively in mutants at 2nd week of age. At 2nd-4th month of age there are no normal hair follicles in shedding regions. Some dermal cysts are found at that period. The dermis is thicker in shedding regions than in haired ones (Sorokina J.D., Blandova Z.K. In: Laboratory Animals Biological Characteristics and Experimental Data Extrapolation for Man. Moscow, 1980, pp 79-80). |
