| Primary Identifier | MGI:1856648 | Allele Type | Spontaneous |
| Gene | Soat1 | Inheritance Mode | Recessive |
| Strain of Origin | AKR/O | Is Recombinase | false |
| Is Wild Type | false |
| description | All AKR sublines are homozygous for Soat1 |
| molecularNote | Deletion of 118 bp in the a Soat1 mRNA. This region corresondes to the 5'UTR and the initial coding sequences. In addition, two missense mutations were observed: A1248G resulting in Ile to Val at amino acid 147 and C1422T resulting in His to Tyr at amino acid 205. Other nucleotide differences were observed that did not result in amino acid changes. A truncated protein is expressed from this allele, presumably due to internal initiation. |
