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Publication : Progressive ankylosis, a new skeletal mutation in the mouse.

First Author  Sweet HO Year  1981
Journal  J Hered Volume  72
Issue  2 Pages  87-93
PubMed ID  7276519 Mgi Jnum  J:6580
Mgi Id  MGI:55055 Doi  10.1093/oxfordjournals.jhered.a109459
Citation  Sweet HO, et al. (1981) Progressive ankylosis, a new skeletal mutation in the mouse. J Hered 72(2):87-93
abstractText  Progressive ankylosis, ank, a new recessive skeletal mutation causing a noninflammatory joint disease in mice is described. Preliminary observations suggest that three abnormal processes are involved: increased calcification of calcified cartilage and of joint tissues, hyperplasia of the cells and tissues of the joints, and degeneration within and around the tissues, tendons, and ligaments of the joints. The new mutation is closely linked, with about 4 percent recombination, to underwhite on chr 15.
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