| Primary Identifier | MGI:1857043 | Allele Type | Spontaneous |
| Attribute String | Null/knockout | Gene | Muc19 |
| Inheritance Mode | Recessive | Strain of Origin | NFS/N |
| Is Recombinase | false | Is Wild Type | false |
| description | In order to be a model for Sjogren syndrome mice must be homozygous for sld and have had a thymectomy at 3 days of age (J:20364) |
| molecularNote | A spontaneous mutation inserted two CA repeats in intron 53 that results in decreased transcript stability. Additional mutations include: insertion of two GA repeats within intron 18, insertion of two T residues within intron 57 and a putative site within intron 52 of an TA repeat region that was intractable to sequencing. RT-PCR confirmed the absence of transcript expression in the sublingual gland. |
