| First Author | Laemle LK | Year | 1995 |
| Journal | Brain Res | Volume | 688 |
| Issue | 1-2 | Pages | 203-8 |
| PubMed ID | 8542309 | Mgi Jnum | J:109913 |
| Mgi Id | MGI:3630089 | Doi | 10.1016/0006-8993(95)00507-m |
| Citation | Laemle LK, et al. (1995) Diurnal variations in vasoactive intestinal polypeptide-like immunoreactivity in the suprachiasmatic nucleus of congenitally anophthalmic mice. Brain Res 688(1-2):203-8 |
| abstractText | The present study has combined recording of circadian locomotor rhythms with light microscopic immunocytochemistry for vasoactive intestinal polypeptide (VIP) in the suprachiasmatic nucleus (SCN) of congenitally anophthalmic mice. These mice, which never develop retinae or optic nerves and do not perceive light, are thus in constant darkness. Our data show a circadian rhythm in expression of VIP in the SCN of anophthalmic mice--expression is maximal during late subjective night/early subjective day and minimal in late subjective day/early subjective night. These observations support the hypothesis that expression of VIP is related to regulation of circadian rhythms by the SCN. |
