| First Author | Guenet JL | Year | 1981 |
| Journal | J Hered | Volume | 72 |
| Issue | 6 | Pages | 440-1 |
| PubMed ID | 6801109 | Mgi Jnum | J:6711 |
| Mgi Id | MGI:55184 | Doi | 10.1093/oxfordjournals.jhered.a109554 |
| Citation | Guenet JL, et al. (1981) Fragilitas ossium: a new autosomal recessive mutation in the mouse. J Hered 72(6):440-1 |
| abstractText | Fragilitas ossium, fro, is an often lethal recessive mutation that was discovered in a randombred stock of mice after treatment with the chemical mutagen tris(1-aziridinyl) phosphine-sulphine. The fro/fro mice have osteoporosis-bending and fracture of the long bones-that is associated with apparently normal cartilage growth. The roentgenological and pathological features are similar to those of the severe, often lethal recessive form of human osteogenesis imperfecta. |
