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Publication : Ovulation rate and pre- and postimplantation survival in mice with a major gene for rapid postweaning gain.

First Author  Dilts RB Year  1991
Journal  J Anim Sci Volume  69
Issue  9 Pages  3590-6
PubMed ID  1938644 Mgi Jnum  J:601
Mgi Id  MGI:49137 Doi  10.2527/1991.6993590x
Citation  Dilts RB, et al. (1991) Ovulation rate and pre- and postimplantation survival in mice with a major gene for rapid postweaning gain. J Anim Sci 69(9):3590-6
abstractText  Differences in ovulation rate, embryo survival, litter size, and fertility are presented for four lines of mice that have been selected for growth or are homozygous for a recessive gene (hg) imparting rapid postweaning gain. Two of the lines were hg/hg, one in a growth-neutral and one in a growth-selected background. The remaining two were Hg/Hg (the corresponding normal, dominant allele with no effect on postweaning gain) in the same two backgrounds. Average ovulation rates ranged from 10.9 to 17.1 eggs shed, and litter sizes ranged from 8.6 to 14.0. In the growth-selected background, the hg allele reduced the number of ovulations, implantation, and litter size by nearly three compared with the Hg/Hg controls. The impact of the hg allele in the growth-neutral background was not significant. When males of a different line selected for high litter size were mated to females of the four stocks, more than two additional eggs, implants, and pups were recorded, compared with results of mating to males of the same line as the female.
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