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Publication : Vacuolated lens

First Author  Dickie MM Year  1967
Journal  Mouse News Lett Volume  36
Pages  39-40 Mgi Jnum  J:13464
Mgi Id  MGI:61654 Citation  Dickie MM (1967) Vacuolated lens. Mouse News Lett 36:39-40
abstractText  Full text of MNL contribution: Vacuolated lens is a recessive mutation which arose in the C3HeB/FeJ strain in January, 1964. Affected animals have white or opaque lenses, may have a belly spot, and may have caudal spina bifida. Although the lens defect is the most. consistent landmark of this mutant, occasionally homozygotes have only a belly spot. Histological study of the lens shows that at birth there are small vacuoles in the lens. The spina bifida is apparent in all embryos at 11 to 12 days of gestation, but is visible in only about 1/3 to 1/2 the affecte d animals at birth. If this defect is not too severe, the lesion heals and the animal survives. Linkage tests are in progress. Suggested symbol for this mutant is vl.
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