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Allele : Tcrd<tm1Mom> T cell receptor delta chain; targeted mutation 1, Peter Mombaerts
Primary Identifier  MGI:1857257 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tcrd
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene cassette was used to disrupt the constant gene segment (designated C-delta). Flow cytometry showed that cells isolated from the lymphoid or epithelial organs of homozygous mice did not react with an anti-pan Tcrd mAb. Immunoprecipitation showed an absence of expression on the surface of thymocytes isolated from homozygous mutant embryos.
  • mutations:
  • Insertion
  • synonyms:
  • delta<0>,
  • delta<0>,
  • C-delta-,
  • TCRdelta-,
  • gammadelta TCR<->,
  • TCRdelta KO,
  • delta<->,
  • TCRdelta-,
  • C-delta-,
  • TCRdelta KO,
  • delta<->,
  • gammadelta TCR<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

20 Carried By

0 Driven By

593 Publication categories





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