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Publication : Mutations in snail family genes enhance craniosynostosis of Twist1 haplo-insufficient mice: implications for Saethre-Chotzen Syndrome.

First Author  Oram KF Year  2005
Journal  Genetics Volume  170
Issue  2 Pages  971-4
PubMed ID  15802514 Mgi Jnum  J:99331
Mgi Id  MGI:3581996 Doi  10.1534/genetics.105.041277
Citation  Oram KF, et al. (2005) Mutations in Snail Family Genes Enhance Craniosynostosis of Twist1 Haplo-insufficient Mice: Implications for Saethre-Chotzen Syndrome. Genetics 170(2):971-4
abstractText  In Drosophila, mutations in the Twist gene interact with mutations in the Snail gene. We show that the mouse Twist1 mutation interacts with Snai1 and Snai2 mutations to enhance aberrant cranial suture fusion, demonstrating that genetic interactions between genes of the Twist and Snail families have been conserved during evolution.
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