| Primary Identifier | MGI:1856915 | Allele Type | Transgenic |
| Gene | Invs | Inheritance Mode | Recessive |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| description | This is the only situs inversus mutation in which the asymmetries occur 100% of the time. Transgenic complementation studies demonstrated that the Invs gene alone corrects the inv mutation, and should be considered the gene responsible for the inv phenotype (J:49759, J:50117). |
| molecularNote | The inv mutation was caused by a transgene insertion mutagenic event that resulted in a small duplication and a 47-kb deletion. This deletion eliminated exons 3-11, causing a frameshift in the remaining coding segment. |
