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Allele : Btk<tm1Wk> Bruton agammaglobulinemia tyrosine kinase; targeted mutation 1, Wasif Kahn

Primary Identifier  MGI:1857138 Allele Type  Targeted
Attribute String  Null/knockout Gene  Btk
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing exons 13 and 14 was replaced with a neomycin resistance cassette. These sequences encode the beginning of the kinase domain.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Btk-,
  • Btk<M>,
  • Btk-kin<->/GL,
  • Btk<M>,
  • Btk-kin<->/GL,
  • Btk-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

86 Publication categories