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Allele : Agtr1a<tm1Unc> angiotensin II receptor, type 1a; targeted mutation 1, University of North Carolina
Primary Identifier  MGI:1857147 Allele Type  Targeted
Attribute String  Null/knockout Gene  Agtr1a
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  Kidneys of these null receptor mice are normal except for some expansion of renin-producing cells (J:45507).
molecularNote  A 0.5kb genomic fragment containing part of the coding sequences of the gene was replaced with a neomycin selection cassette. Binding studies in kidney indicated that no functional protein was detectable in homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • At1A-,
  • Agtr1A-,
  • Agtr1<tm1Unc>,
  • Agt1ar<->,
  • Agtr1<tm1Unc>,
  • AT1-R-,
  • At1A-,
  • AT1A-KO,
  • Agt1ar<->,
  • AT1aR<->,
  • AT1AR KO,
  • Agtr1A-,
  • AT1aR<->,
  • AT1AR KO,
  • AT1A-KO,
  • AT1-R-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

141 Publication categories





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