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Allele : Fmr1<tm1Cgr> fragile X messenger ribonucleoprotein 1; targeted mutation 1, Ben Oostra

Primary Identifier  MGI:1857169 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fmr1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  Genbank: AF179463 and AF170530
molecularNote  A neomycin resistance gene was inserted into exon 5. RT-PCR analysis on testis RNA derived from hemizygous male mice demonstrated that no detectable transcript was produced from this allele, and western blot analysis on extracts of testes, liver, kidney and brain of hemizygous male mice confirmed that no stable encoded protein was made.
  • mutations:
  • Insertion
  • synonyms:
  • FMRP KO,
  • Fmr1 KO,
  • Fmr1 KO,
  • FMRP KO,
  • fmr-tm1Cgr,
  • Fmr1<tm4Cgr>,
  • fmr-tm1Cgr,
  • FraX,
  • Fmr1<tm4Cgr>,
  • FraX
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

11 Carried By

0 Driven By

608 Publication categories