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Publication : Motor abnormalities in lurcher mutant mice.

First Author  Lalonde R Year  1992
Journal  Physiol Behav Volume  51
Issue  3 Pages  523-5
PubMed ID  1523229 Mgi Jnum  J:990
Mgi Id  MGI:49522 Doi  10.1016/0031-9384(92)90174-z
Citation  Lalonde R, et al. (1992) Motor abnormalities in lurcher mutant mice. Physiol Behav 51(3):523-5
abstractText  Lurcher mutants had deficits in equilibrium in the coat-hanger and grid tests but not the wooden beam test. Although the mutants had less hole-pokes when confronted with small holes in most conditions, they had more hole-pokes with larger holes, demonstrating perseverative behavior. There was no decrease in rearing responses. These results indicate that in spite of cerebellar degeneration and ataxia, lurcher mutants are not impaired in all tests measuring motor function.
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