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Publication : Hole poking and motor coordination in lurcher mutant mice.

First Author  Lalonde R Year  1993
Journal  Physiol Behav Volume  54
Issue  1 Pages  41-4
PubMed ID  8327607 Mgi Jnum  J:15999
Mgi Id  MGI:64095 Doi  10.1016/0031-9384(93)90041-d
Citation  Lalonde R, et al. (1993) Hole poking and motor coordination in lurcher mutant mice. Physiol Behav 54(1):41-4
abstractText  Lurcher mutant mice, a cerebellar mutant displaying ataxia and equilibrium deficits, had fewer hole pokes in a 16-hole matrix than normal mice. Lurcher mutants also took longer to reach a platform from a grid and to begin to climb a grid from the floor. However, the lurchers climbed as high as normal mice on the grid and their exploratory patterns of the holeboard were similar in many respects to normal mice, such as the ratio of center to peripheral hole exploration. In a wooden beam test, although lurchers did not differ from normal mice in terms of the amount of time spent on the beam or in the distance travelled, the mutants were found more often in unstable positions.
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