First Author | Caston J | Year | 1998 |
Journal | Brain Res | Volume | 808 |
Issue | 2 | Pages | 232-7 |
PubMed ID | 9767169 | Mgi Jnum | J:107881 |
Mgi Id | MGI:3622410 | Doi | 10.1016/s0006-8993(98)00847-6 |
Citation | Caston J, et al. (1998) Role of the cerebellum in exploration behavior. Brain Res 808(2):232-7 |
abstractText | Compared to +/+ mice, Lurcher (+/Lc) mutant mice whose cerebellar cortex is lacking almost all Purkinje cells and granule cells, exhibit a low level of exploration; this deficit is not due to a low level of activity but to both a decreased motivation to explore a novel environment and to spatial deficits. The characteristics of exploration in cerebellectomized +/+ and +/Lc mice suggest that the cerebellum is involved not only in cognitive but also in motivational processes. |