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Publication : Role of the cerebellum in exploration behavior.

First Author  Caston J Year  1998
Journal  Brain Res Volume  808
Issue  2 Pages  232-7
PubMed ID  9767169 Mgi Jnum  J:107881
Mgi Id  MGI:3622410 Doi  10.1016/s0006-8993(98)00847-6
Citation  Caston J, et al. (1998) Role of the cerebellum in exploration behavior. Brain Res 808(2):232-7
abstractText  Compared to +/+ mice, Lurcher (+/Lc) mutant mice whose cerebellar cortex is lacking almost all Purkinje cells and granule cells, exhibit a low level of exploration; this deficit is not due to a low level of activity but to both a decreased motivation to explore a novel environment and to spatial deficits. The characteristics of exploration in cerebellectomized +/+ and +/Lc mice suggest that the cerebellum is involved not only in cognitive but also in motivational processes.
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