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Allele : Nodal<TgR(MPSVNeo)413.dRob> nodal growth differentiation factor; retroviral transgene insertion, Elizabeth J Robertson

Primary Identifier  MGI:1856970 Allele Type  Transgenic
Attribute String  Null/knockout Gene  Nodal
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129S/SvEv-Gpi1<c> Is Recombinase  false
Is Wild Type  false
molecularNote  A chimeric animal derived from ES cells that were infected with a MPSVmos-1 Neo retroviral vector was shown to have a insertional mutation event in the first intron of the gene. Northern blot analysis on homozygous cell lines confirmed that the mutation interfered with the normal transcription of this gene.
  • mutations:
  • Viral insertion
  • synonyms:
  • nodal,
  • 413.d,
  • nodal,
  • Nodal<Tg413.d>,
  • Nodal<Tg413.d>,
  • 413.d
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

15 Publication categories