| Primary Identifier | MGI:1857007 | Allele Type | Spontaneous |
| Gene | ptr | Inheritance Mode | Recessive |
| Strain of Origin | (C57BL/Fa x A/Fa)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | Strain differences in resistance to urethan-induced lung tumors were first noted by Cowen (J:232) who showed that the major part of the difference between the susceptible A and resistant C57BL strains was due to a single locus with susceptibility dominant. In a more extensive analysis, Bloom and Falconer (J:13102) found the same strain distribution of susceptibility and confirmed the single-locus difference between strains A and C57BL. The recessive gene for resistance in C57BL was designated ptr (J:232). The ptr gene may be identical with the resistance allele at the Pas1 locus described by Malkinson et al. (J:8075). |
