|  Help  |  About  |  Contact Us

Allele : Gfap<tm1Mes> glial fibrillary acidic protein; targeted mutation 1, Albee Messing

Primary Identifier  MGI:1857176 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gfap
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette replaced most of exon 1 and all of exons 2-4. Northern blot analysis revealed that there was no mRNA produced from this allele in whole brain RNA samples derived from homozygous mice. Immunohistochemical studies detected no GFAP protein present in sections of hippocampus in homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

12 Publication categories