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Allele : Hexa<tm1Rlp> hexosaminidase A; targeted mutation 1, Richard L Proia

Primary Identifier  MGI:1857181 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hexa
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette was inserted into and disrupted exon 8 of the gene. Northern blots of liver homogenates from homozygous mutant mice showed no detectable transcript. This mutation resulted in the production of no detectable functional protein.
  • mutations:
  • Insertion
  • synonyms:
  • Tay-Sachs hexa<->,
  • Hexa<->,
  • Tay-Sachs,
  • Tay-Sachs hexa<->,
  • Hexa<->,
  • Tay-Sachs
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

15 Publication categories