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Publication : Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants.

First Author  Texidó G Year  1996
Journal  Eur J Immunol Volume  26
Issue  8 Pages  1966-9
PubMed ID  8765046 Mgi Jnum  J:34589
Mgi Id  MGI:82044 Doi  10.1002/eji.1830260843
Citation  Texido G, et al. (1996) Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants. Eur J Immunol 26(8):1966-9
abstractText  We show through sequence analysis of rearranged immunoglobulin variable (Ig-V) region genes from memory B cells of mouse mutants generated by gene targeting that terminal deoxynucleotidyl transferase, CD23, interleukin- 4, IgD and CD30 are dispensable for somatic hypermutation.
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