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Allele : Cd74<tm2Liz> CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); targeted mutation 2, Elizabeth K Bikoff

Primary Identifier	MGI:1857190	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cd74
Transmission	Germline	Strain of Origin	129S/SvEv-Gpi1<c>
Is Recombinase	false	Is Wild Type	false

molecularNote

Deletion of exon 6b results in expression of the p31 isoform but not p41.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
31,
31

earliestPublication:
Takaesu NT, et al. (1995) Major histocompatibility class II peptide occupancy, antigen presentation, and CD4+ T cell function in mice lacking the p41 isoform of invariant chain. Immunity 3(3):385-96

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

10 Publication categories

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