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Allele : Il2rb<tm1Mak> interleukin 2 receptor, beta chain; targeted mutation 1, Tak Mak
Primary Identifier  MGI:1857193 Allele Type  Targeted
Attribute String  Null/knockout Gene  Il2rb
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  Mice were generated from two independent embryonic stem cell lines: D3, derived from 129S2/SvPas; and E14, derived from 129P2/OlaHsd. (J:25940) Experiments described in J:25940 were performed using mice derived from the D3 ES cell line.
molecularNote  Insertion of a neomycin resistance cassette disrupted exon 6 of the gene, which encodes a region of extracellular domain proximal to the transmembrane region of the protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CD122<->,
  • CD122<->,
  • Il2rb<->,
  • IL-2Rbeta-,
  • Il2rb<->,
  • 2Rbeta-,
  • 2Rbeta-,
  • IL-2/IL-15Rbeta-,
  • IL-2/IL-15Rbeta-,
  • IL-2Rbeta-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

11 Carried By

0 Driven By

70 Publication categories





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