First Author | Hryniewicz A | Year | 2007 |
Journal | Eur J Pharmacol | Volume | 577 |
Issue | 1-3 | Pages | 219-20 |
PubMed ID | 17920057 | Mgi Jnum | J:139627 |
Mgi Id | MGI:3808980 | Doi | 10.1016/j.ejphar.2007.08.046 |
Citation | Hryniewicz A, et al. (2007) Impairment of recognition memory in interleukin-6 knock-out mice. Eur J Pharmacol 577(1-3):219-20 |
abstractText | We have used transgenic male mice not expressing interleukin-6 (IL-6) [C57BL/6J(IL-6/-tm Kopf)] in object recognition test to assess the role of endogenous IL-6 in recognition memory. Wild-type controls showed better memory than IL-6 knock-out mice. Results of our experiment suggest that endogenous IL-6 may play an important role in the process of recognition memory in mice. |