First Author | Andersen YS | Year | 2006 |
Journal | Infect Immun | Volume | 74 |
Issue | 4 | Pages | 2473-6 |
PubMed ID | 16552082 | Mgi Jnum | J:107409 |
Mgi Id | MGI:3621097 | Doi | 10.1128/IAI.74.4.2473-2476.2006 |
Citation | Andersen YS, et al. (2006) Adaptive immunity-dependent intestinal hypermotility contributes to host defense against Giardia spp. Infect Immun 74(4):2473-6 |
abstractText | Humans infected with Giardia exhibit intestinal hypermotility, but the underlying mechanisms and functional significance are uncertain. Here we show in murine models of giardiasis that small-intestinal hypermotility occurs in a delayed fashion relative to peak parasite burden, is dependent on adaptive immune defenses, and contributes to giardial clearance. |