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Allele : Nos2<tm1Lau> nitric oxide synthase 2, inducible; targeted mutation 1, Victor E Laubach
Primary Identifier  MGI:1857228 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nos2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette replaced exons 12 and 13 of the gene, which encode the calmodulin-binding domain. Northern and Western blots of IFNg/LPS-stimulated peritoneal macrophages showed no detectable Nos2 mRNA or protein, respectively.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • iNOS<->,
  • iNOS-,
  • iNOS KO,
  • NOS2-,
  • NOS2-,
  • NOS2<tm/Lau>,
  • iNOS KO,
  • iNOS<->,
  • Nos2tm1Lau,
  • iNOS-,
  • NOS2<tm/Lau>,
  • Nos2tm1Lau
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

15 Carried By

0 Driven By

513 Publication categories





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