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Allele : Ccnd1<tm1Wbg> cyclin D1; targeted mutation 1, Robert A Weinberg

Primary Identifier  MGI:1857280 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ccnd1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A genomic fragment containing part of exon 1, exon 2 and exon 3 was replaced with a neomycin selection cassette. The deleted sequences encode the cyclin box domain thought to be required for protein activity. Western blot analysis on embryonic fibroblasts derived from homozygous mice confirmed that no stable protein was made from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Ccnd1<1-3->,
  • Ccnd1<delta1-3>,
  • Ccnd1<1-3->,
  • cyclin D1-,
  • CD1<->,
  • Ccnd1<delta1-3>,
  • cyclin D1-,
  • CD1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

66 Publication categories