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Allele : Cybb<tm1Din> cytochrome b-245, beta polypeptide; targeted mutation 1, Mary C Dinauer

Primary Identifier  MGI:1857284 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cybb
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 3. Western blot analysis on extracts of neutrophil-rich peritoneal exudate cells from hemizygous male mice confirmed that no detectable protein was expressed.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Nox-2<->,
  • gp91phox<->,
  • gp91<phox>,
  • Cybbtm1Din,
  • X-CGD,
  • NOX2<->,
  • Nox2<->,
  • gp91-,
  • Nox2<->,
  • gp91phox<->,
  • Cybb<tm1>,
  • NOX2<->,
  • Cybb KO,
  • gp91<phox->,
  • Cybb<tm1>,
  • gp91<phox>,
  • PHOX<->,
  • gp91<phox->,
  • X-CGD,
  • Cybbtm1Din,
  • PHOX<->,
  • gp91-,
  • Nox-2<->,
  • Cybb KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

559 Publication categories