Primary Identifier | MGI:1857291 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Plg |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A PGK-HPRT minigene replaces proximal promoter sequences and the first two exons of the gene. Northern analysis and enzymatic activity assays were used to demonstrate the lack of a transcript and functional protein, respectively, in homozygous mutant animals. |